{"id":131,"date":"2017-07-05T21:24:48","date_gmt":"2017-07-05T19:24:48","guid":{"rendered":"http:\/\/mttlab.eu\/?page_id=131"},"modified":"2018-09-13T20:46:41","modified_gmt":"2018-09-13T18:46:41","slug":"in-vivo-services","status":"publish","type":"page","link":"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/","title":{"rendered":"In Vivo Services"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>MTTlab specializes in carrying out and evaluating preclinical tests of novel oncological compounds and medical devices. MTTlab offers small\/medium size (up to 500 mice in a single experiment) in vivo studies (toxicology, efficacy, behavioural, disease models, biodistribution) and relevant in vitro studies.<\/p>\n<h5><strong>In vivo oncology testing<\/strong><\/h5>\n<p>MTTlab offers following experimental models:<\/p>\n<ul>\n<li>Xenografts<\/li>\n<li>Allografts<\/li>\n<li>Metastasis, Leukemia and Lymphoma,<\/li>\n<li>Orthotopic Experiments upon request (not included in the flat rate package)<\/li>\n<li>Toxicology Testing DRF in mice.<\/li>\n<\/ul>\n<p>Please enquire for more extended toxicology studies.<\/p>\n<p>Various <em>in vivo<\/em> tumor models are available. All <em>in vivo<\/em> tumor experiments use tumor fragment-based technology or <em>in vivo<\/em> propagated (i.p.) tumors. Each animal is identified via micro-chip and randomization into experimental groups is performed according to the highest standards.<\/p>\n<p>In standard experiments, 7 to 15 mice are used per test group and each experiment includes a vehicle and selected chemotherapeutic control groups. As per sponsor request, smaller groups and\/or more diverse compounds can be tested in a single Study. MTTlab calculates the study cost according to the number of mice and no setup fee is added.<\/p>\n<h5><strong>Metabolomics and NMR applied to in vivo studies:<\/strong><\/h5>\n<p>Thank to collaborate with Giotto Biotech Srl, MTTlab offers the following services:<\/p>\n<ul>\n<li>NMR screening and metabolomics of biological fluids, tissue and food products<\/li>\n<li>Metabolomic profiling and disease fingerprinting<\/li>\n<li>Biomarker discovery<\/li>\n<li>Drug studies (toxicity, mechanism of action, side effect)<\/li>\n<li>Metabolomic statistical analysis<\/li>\n<\/ul>\n<h5><strong>Molecular pharmacology applied to in vivo studies:<\/strong><\/h5>\n<p>Thanks to collaboration with Vivomicx, MTTlab offers the following services:<\/p>\n<ul>\n<li>molecular pharmacology of your drug in <a href=\"https:\/\/mttlab.eu\/wp-content\/uploads\/2018\/09\/Vivomicx-MTTlab-molecular-pharmacology.pdf\">tissue compartments<\/a><\/li>\n<li>identification and validation of molecular targets<\/li>\n<li>biomarker identification and validation<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; MTTlab specializes in carrying out and evaluating preclinical tests of novel oncological compounds and medical devices. MTTlab offers small\/medium size (up to 500 mice in a single experiment) in vivo studies (toxicology, efficacy, behavioural, disease models, biodistribution) and relevant in vitro studies. In vivo oncology testing MTTlab offers following experimental models: Xenografts Allografts Metastasis,&hellip; <br \/> <a class=\"button small blue\" href=\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"jetpack_post_was_ever_published":false,"footnotes":""},"class_list":["post-131","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>In Vivo Services - MTTlab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"In Vivo Services - MTTlab\" \/>\n<meta property=\"og:description\" content=\"&nbsp; MTTlab specializes in carrying out and evaluating preclinical tests of novel oncological compounds and medical devices. MTTlab offers small\/medium size (up to 500 mice in a single experiment) in vivo studies (toxicology, efficacy, behavioural, disease models, biodistribution) and relevant in vitro studies. In vivo oncology testing MTTlab offers following experimental models: Xenografts Allografts Metastasis,&hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/\" \/>\n<meta property=\"og:site_name\" content=\"MTTlab\" \/>\n<meta property=\"article:modified_time\" content=\"2018-09-13T18:46:41+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/\",\"url\":\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/\",\"name\":\"In Vivo Services - MTTlab\",\"isPartOf\":{\"@id\":\"https:\/\/mttlab.eu\/#website\"},\"datePublished\":\"2017-07-05T19:24:48+00:00\",\"dateModified\":\"2018-09-13T18:46:41+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/mttlab.eu\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"In Vivo Services\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/mttlab.eu\/#website\",\"url\":\"https:\/\/mttlab.eu\/\",\"name\":\"MTTlab\",\"description\":\"Expand your research\",\"publisher\":{\"@id\":\"https:\/\/mttlab.eu\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/mttlab.eu\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/mttlab.eu\/#organization\",\"name\":\"MTTlab\",\"url\":\"https:\/\/mttlab.eu\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/mttlab.eu\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/i0.wp.com\/mttlab.eu\/wp-content\/uploads\/2017\/07\/SmallLogo_233x70px.png?fit=233%2C70&ssl=1\",\"contentUrl\":\"https:\/\/i0.wp.com\/mttlab.eu\/wp-content\/uploads\/2017\/07\/SmallLogo_233x70px.png?fit=233%2C70&ssl=1\",\"width\":233,\"height\":70,\"caption\":\"MTTlab\"},\"image\":{\"@id\":\"https:\/\/mttlab.eu\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.linkedin.com\/company\/mttlab-srl\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"In Vivo Services - MTTlab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/mttlab.eu\/index.php\/in-vivo-services\/","og_locale":"en_US","og_type":"article","og_title":"In Vivo Services - MTTlab","og_description":"&nbsp; MTTlab specializes in carrying out and evaluating preclinical tests of novel oncological compounds and medical devices. 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